Comparing time activity curves using the Akaike information criterion.
Identifieur interne : 001F89 ( Main/Exploration ); précédent : 001F88; suivant : 001F90Comparing time activity curves using the Akaike information criterion.
Auteurs : RBID : pubmed:19820266English descriptors
- KwdEn :
- Adult, Aged, Antigens, CD (chemistry), Cell Adhesion Molecules (chemistry), Female, Humans, Indium Radioisotopes (pharmacokinetics), Kinetics, Leukemia, Myeloid, Acute (radiotherapy), Male, Middle Aged, Models, Statistical, Precursor Cell Lymphoblastic Leukemia-Lymphoma (radiotherapy), Radiometry (methods), Radiopharmaceuticals (pharmacokinetics), Yttrium Radioisotopes (pharmacokinetics).
- MESH :
- chemical , chemistry : Antigens, CD, Cell Adhesion Molecules.
- chemical , pharmacokinetics : Indium Radioisotopes, Radiopharmaceuticals, Yttrium Radioisotopes.
- methods : Radiometry.
- radiotherapy : Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma.
- Adult, Aged, Female, Humans, Kinetics, Male, Middle Aged, Models, Statistical.
Abstract
The comparison of curves is a common task in many fields of science. Simply comparing the sums of squares or R(2) is not sufficient, and frequently used tests have many disadvantages. The basic idea of the presented method is turning the problem of comparing curves into a problem of model selection using the corrected Akaike Information Criterion. Here, this straightforward approach is applied for comparing curves using the example of (111)In- and (90)Y-labelled anti-CD66 antibody serum time activity data. As a result it is shown that for the investigated (111)In- and (90)Y-labelled anti-CD66 antibodies, the biokinetics between dosimetry and therapy are different with respect to the contribution of the second, longer half-life component. We advocate the use of the presented method rather than employing less advanced approaches for curve comparison.
DOI: 10.1088/0031-9155/54/21/N01
PubMed: 19820266
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comparing time activity curves using the Akaike information criterion.</title><author><name sortKey="Kletting, Peter" uniqKey="Kletting P">Peter Kletting</name><affiliation wicri:level="3"><nlm:affiliation>Klinik für Nuklearmedizin, Universität Ulm, Ulm, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik für Nuklearmedizin, Universität Ulm, Ulm</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Ulm</settlement></placeName></affiliation></author><author><name sortKey="Kull, Thomas" uniqKey="Kull T">Thomas Kull</name></author><author><name sortKey="Reske, Sven N" uniqKey="Reske S">Sven N Reske</name></author><author><name sortKey="Glatting, Gerhard" uniqKey="Glatting G">Gerhard Glatting</name></author></titleStmt><publicationStmt><date when="2009">2009</date><idno type="doi">10.1088/0031-9155/54/21/N01</idno><idno type="RBID">pubmed:19820266</idno><idno type="pmid">19820266</idno><idno type="wicri:Area/Main/Corpus">001C64</idno><idno type="wicri:Area/Main/Curation">001C64</idno><idno type="wicri:Area/Main/Exploration">001F89</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Antigens, CD (chemistry)</term><term>Cell Adhesion Molecules (chemistry)</term><term>Female</term><term>Humans</term><term>Indium Radioisotopes (pharmacokinetics)</term><term>Kinetics</term><term>Leukemia, Myeloid, Acute (radiotherapy)</term><term>Male</term><term>Middle Aged</term><term>Models, Statistical</term><term>Precursor Cell Lymphoblastic Leukemia-Lymphoma (radiotherapy)</term><term>Radiometry (methods)</term><term>Radiopharmaceuticals (pharmacokinetics)</term><term>Yttrium Radioisotopes (pharmacokinetics)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Antigens, CD</term><term>Cell Adhesion Molecules</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Indium Radioisotopes</term><term>Radiopharmaceuticals</term><term>Yttrium Radioisotopes</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Radiometry</term></keywords><keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Leukemia, Myeloid, Acute</term><term>Precursor Cell Lymphoblastic Leukemia-Lymphoma</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Kinetics</term><term>Male</term><term>Middle Aged</term><term>Models, Statistical</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The comparison of curves is a common task in many fields of science. Simply comparing the sums of squares or R(2) is not sufficient, and frequently used tests have many disadvantages. The basic idea of the presented method is turning the problem of comparing curves into a problem of model selection using the corrected Akaike Information Criterion. Here, this straightforward approach is applied for comparing curves using the example of (111)In- and (90)Y-labelled anti-CD66 antibody serum time activity data. As a result it is shown that for the investigated (111)In- and (90)Y-labelled anti-CD66 antibodies, the biokinetics between dosimetry and therapy are different with respect to the contribution of the second, longer half-life component. We advocate the use of the presented method rather than employing less advanced approaches for curve comparison.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">19820266</PMID><DateCreated><Year>2009</Year><Month>10</Month><Day>20</Day></DateCreated><DateCompleted><Year>2010</Year><Month>02</Month><Day>18</Day></DateCompleted><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1361-6560</ISSN><JournalIssue CitedMedium="Internet"><Volume>54</Volume><Issue>21</Issue><PubDate><Year>2009</Year><Month>Nov</Month><Day>7</Day></PubDate></JournalIssue><Title>Physics in medicine and biology</Title><ISOAbbreviation>Phys Med Biol</ISOAbbreviation></Journal><ArticleTitle>Comparing time activity curves using the Akaike information criterion.</ArticleTitle><Pagination><MedlinePgn>N501-7</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1088/0031-9155/54/21/N01</ELocationID><Abstract><AbstractText>The comparison of curves is a common task in many fields of science. Simply comparing the sums of squares or R(2) is not sufficient, and frequently used tests have many disadvantages. The basic idea of the presented method is turning the problem of comparing curves into a problem of model selection using the corrected Akaike Information Criterion. Here, this straightforward approach is applied for comparing curves using the example of (111)In- and (90)Y-labelled anti-CD66 antibody serum time activity data. As a result it is shown that for the investigated (111)In- and (90)Y-labelled anti-CD66 antibodies, the biokinetics between dosimetry and therapy are different with respect to the contribution of the second, longer half-life component. We advocate the use of the presented method rather than employing less advanced approaches for curve comparison.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kletting</LastName><ForeName>Peter</ForeName><Initials>P</Initials><Affiliation>Klinik für Nuklearmedizin, Universität Ulm, Ulm, Germany.</Affiliation></Author><Author ValidYN="Y"><LastName>Kull</LastName><ForeName>Thomas</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Reske</LastName><ForeName>Sven N</ForeName><Initials>SN</Initials></Author><Author ValidYN="Y"><LastName>Glatting</LastName><ForeName>Gerhard</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Journal Article</PublicationType><PublicationType>Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2009</Year><Month>10</Month><Day>09</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Phys Med Biol</MedlineTA><NlmUniqueID>0401220</NlmUniqueID><ISSNLinking>0031-9155</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Antigens, CD</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>CD66 antigens</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Cell Adhesion Molecules</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Indium Radioisotopes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Radiopharmaceuticals</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Yttrium Radioisotopes</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Antigens, CD</DescriptorName><QualifierName MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Cell Adhesion Molecules</DescriptorName><QualifierName MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName><QualifierName MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Kinetics</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Leukemia, Myeloid, Acute</DescriptorName><QualifierName MajorTopicYN="N">radiotherapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Models, Statistical</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Precursor Cell Lymphoblastic Leukemia-Lymphoma</DescriptorName><QualifierName MajorTopicYN="N">radiotherapy</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Radiometry</DescriptorName><QualifierName MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Radiopharmaceuticals</DescriptorName><QualifierName MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Yttrium Radioisotopes</DescriptorName><QualifierName MajorTopicYN="N">pharmacokinetics</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="aheadofprint"><Year>2009</Year><Month>10</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>10</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>10</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>2</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">S0031-9155(09)25291-2</ArticleId><ArticleId IdType="doi">10.1088/0031-9155/54/21/N01</ArticleId><ArticleId IdType="pubmed">19820266</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=IndiumV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001F89 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001F89 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= *** parameter Area/wikiCode missing ***
|area= IndiumV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:19820266
|texte= Comparing time activity curves using the Akaike information criterion.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:19820266" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a IndiumV2
| This area was generated with Dilib version V0.5.76. |  |